Zitat von: HAL9000 am 28. Dezember 2025, 17:13:17Für mich eher zwiespältig, ob "vermissen" gerechtfertigt ist.
Sie ist ein Beweis, dass mit dem Alter nicht immer Weisheit kommt.
Ihre rechtsradikalen, ausländerfeindlichen Entgleisungen haben ihr
Vermächtnis mMn mächtig getrübt.
Zitat von: Schwuppdiwupp am 28. Dezember 2025, 20:57:58Wenn jemand einen Beweis dafür brauchen sollte, dass biologische Männer biologischen Frauen körperlich haushoch überlegen sind, dem sei dieses absolut sinnlose Tennis-Spiel als Anschauungsmaterial empfohlen.



Zitat[...] This review outlines the essential role of mitochondria by considering the numerous intracellular, extracellular, and physiological functions it regulates that position the organelle as a central mediator in responses to psychological stress. We then connect these functions to mitochondrial allostasis and allostatic load for further examination of the limitations of mitochondria to an adaptive psychological stress response where mitochondrial allostatic load may eventually lead to systemic pathophysiology. [...]
Reid DM et al: Mitochondrial Functioning: Front and Center in Defining Psychosomatic Mechanisms of Allostasis in Health and Disease, in Qing Yan (ed.): Psychoneuroimmunology: Methods and Protocols. 3rd ed., Springer Nature 2025
Zitat von: HAL9000 am 28. Dezember 2025, 10:23:38Gestorben sind die Nager allerdings nicht, sondern reagierten "nur" mit einer Immunsuppression.Ja, das dürfte diese Geschichte sein. Bei WP steht allerdings auch was von verstorbenen Nagern. Ich habe mal räscherschiert. Das ist quasi die Geburtsstunde der (experimentellen) Psychoneuroimmunologie (PNI, man erschöpft schon von dem Wort). Der WP-Artikel ist nicht ganz richtig, nur so halbwegs, man verwechselt ein paar Dinge bzw. würfelt was falsch zusammen. Man findet die Hinweise beim entsprechenden Eintrag zur PNI. Die erste richtige Studie stammt aus 1975:
ZitatBehaviorally conditioned immunosuppressionhttps://pubmed.ncbi.nlm.nih.gov/1162023/
R Ader, N Cohen
PMID: 1162023 DOI: 10.1097/00006842-197507000-00007
Abstract
An illness-induced taste aversion was conditioned in rats by pairing saccharin with cyclophosphamide, an immunosuppressive agent. Three days after conditioning, all animals were injected with sheep erythrocytes. Hemagglutinating antibody titers measured 6 days after antigen administration were high in placebo-treated rats. High titers were also observed in nonconditioned animals and in conditioned animals that were nor subsequently exposed to saccharin. No agglutinating antibody was detected in conditioned animals treated with cyclophosphamide at the time of antigen administration. Conditioned animals exposed to saccharin at the time of or following the injection of antigen were significantly immunosuppressed. An illness-induced taste aversion was also conditioned using LiCl, a nonimmunosuppressive agent. In this instance, however, there was no attenuation of hemagglutinating antibody titers in response to injection with antigen.
). Man findet das in einem Nachruf seiner Wirkstätte:Zitatn the early 1970s, in what would become one of his most distinctive experiments, Dr. Ader was studying taste aversion conditioning in rats. In the experiment, rats drank different volumes of a saccharin solution and also were injected with a dose of Cytoxan, an immunosuppressive drug that induces gastrointestinal upset. The rats "learned" or were conditioned to avoid consuming the solution.https://www.urmc.rochester.edu/news/story/robert-ader-founder-of-psychoneuroimmunology-dies
When he stopped giving the rats the drug but continued to give them the saccharin solution, not only did the rats avoid drinking the solution, some of the animals died. The magnitude of the avoidance response of the rats was directly related to the volume of solution consumed, Dr. Ader found. He also found that the mortality rate also varied with the amount of solution consumed. Dr. Ader believed this orderly relationship could not be due to chance.
ZitatAfter Dr. Ader and Cohen published an article in Science on the conditioned suppression of autoimmunity in mice, a noted immunologist told Cohen that he and his colleagues devoted a journal club to trying to poke holes in the paper. They were not successful and the immunologist stopped being a skeptic.
ZitatThat study, clearly demonstrating that immune responses could be modified by classical conditioning, meant there were connections between the brain and the immune system and that the mind could have profound effects on the body's functions that were thought to be independent.
ZitatImmunologische Botenstoffe im Nervensystem sind hauptsächlich
Zytokine (wie Interleukine, TNF-α) und Neuropeptide (z.B. Substanz P, Opioide), die die Kommunikation zwischen Immunsystem und Gehirn steuern und Verhaltensweisen wie Müdigkeit, Appetitlosigkeit und Fieber auslösen ("Sickness Behavior"), während Neurotransmitter (wie Dopamin, Serotonin) auch von Immunzellen beeinflusst werden und umgekehrt das Immunsystem modulieren, um Entzündungen zu regulieren und Stressreaktionen zu verarbeiten.
Zitat von: Schwuppdiwupp am 28. Dezember 2025, 20:57:58Der Mann gewann mit 6:3 und 6:3 gegen die Frau.Komisch, dabei hat die doch viel lauter und heftiger gestöhnt als der Tüp (den hat man gar nicht gehört). Oder es lag am Gestöhne, da kann man sich schlechter konzentrieren. Achso: so etwas in der Art scheint es regelmäßig zu geben, ich erinnere mich dunkel an ein ähnliches Schauspiel. Beim Boxen ist das genauso, wie man bei Olympia sehen konnte. Diese Tennisturniere scheint man bevorzugt in nicht-
Zitat von: zimtspinne am 27. Dezember 2025, 22:56:04Und das sagen die ach so bösen Republikaner. Quasi Faschisten.
ZitatWhile recent polling shows that a majority of Democratic voters oppose pediatric medical transition, the issue remains intensely polarized among politicians and policymakers. Conservatives and liberals alike can agree that all people, and especially children, deserve ethical, evidence-based care. We recognize that liberals distrust anything coming from the current administration, but we hope they will take the time to read this review and see that it puts science first.